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2022 - 2023

Breast cancer remotely imposes a myeloid bias on hematopoietic stem cells by reprogramming the bone marrow niche.

Gerber-Ferder Y, Cosgrove J, Duperray-Susini A, Missolo-Koussou Y, Dubois M, Sedlik C, Lameiras S, Baulande S, Pierre Guermonprez, Passaro D, Perie L, Piaggio E*; Helft J*, 19 December 2022, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-2338323/v1]

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The Dynamic Interface Between Vascular Blood Vessels to Blood Forming Hematopoietic Stem Cells in Health and Disease.

Itkin T*, Duarte D*, Passaro D*.

Front Cell Dev Biol. 2022 Mar 4;10:870129. doi: 10.3389/fcell.2022.870129. PMID: 35309923; PMCID: PMC8930838.

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2020 - 2021

Integrated OMICs unveil the bone marrow microenvironment in human leukemia.

Passaro D, Garcia-Albornoz M^, Diana G^, Chakravarty P, Ariza-McNaughton L, Batsivari A, Borràs-Eroles C, Abarrategi A, Waclawiczek A, Ombrato L, Malanchi I, Gribben J and Bonnet D.

Cell Reports. 2021 May 11;35(6):109119. doi: 10.1016/j.celrep.2021.109119.

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Bioengineering the bone marrow vascular niche.

Bessy T, Itkin T*, Passaro D*.

Front. Cell Dev. Biol. 2021 Apr 28;9:645496. doi: 10.3389/fcell.2021.645496. eCollection 2021.

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DCE-MRI quantification of leukemia-induced changes in bone marrow vascular function.

Gomes AL, Gribben J, Siow B*, Passaro D* and Bonnet D*.

Haematologica. 2021 Aug 1;106(8):2281-2286. doi: 10.3324/haematol.2020.277269. PMID: 33764000; PMCID: PMC8327741.

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Generation of neighbor-labeling cells to study intercellular interactions in vivo.

Ombrato L, Nolan E  3 , Passaro D, Kurelac I, Bridgeman VL, Waclawiczek A, Duarte D, Lo Celso C, Bonnet D, Malanchi I.

Nat Protoc. 2021 Feb;16(2):872-892. doi: 10.1038/s41596-020-00438-5. Epub 2020 Dec 11.

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Visualizing Cancer.

Krummel M, Hu K, de Vries EGE, Goetz JG, Passaro D, Subramaniam S, Misteli T, Skala M, Bravo-Cordero JJ, Sutcliffe JL.

Cancer Cell. 2020 Dec 14;38(6):753-756. doi: 10.1016/j.ccell.2020.11.014. PMID: 33321083.

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Introductions to the Community: Early-Career Researchers in the Time of COVID-19.

Smith Q, McKinley KL, Chan CJ, Sikandar S, Xiang Y, Passaro D.

Cell Stem Cell. 2020 Nov 5;27(5):702-704. doi: 10.1016/j.stem.2020.10.008. PMID: 33157046

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Myeloid cells hold the master key for T-ALL spread.

Passaro D.

Blood. 2020 Oct 15;136(16):1799-1800. doi: 10.1182/blood.2020007970.
 

Dynamic responses of the haematopoietic stem cell niche to diverse stresses.

Batsivari A*, Haltalli MLR*, Passaro D*, Pospori C*, Lo Celso C^, Bonnet D^.

Nat Cell Biol. 2020 Jan;22(1):7-17. doi: 10.1038/s41556-019-0444-9. Epub 2020 Jan 6. Erratum in: Nat Cell Biol. 2020 Feb;22(2):257. PMID: 31907409

2019 - 2018

How to say NO to vascular disruption and stem cell mobilization.

Passaro D, Bonnet D.

Expert Opin Ther Targets. 2018 Jul;22(7):563-565. doi: 10.1080/14728222.2018.1486821. Epub 2018 Jun 17. No abstract available.

PMID: 29889568

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Modeling the human bone marrow niche in mice: From host bone marrow engraftment to bioengineering approaches.

Abarrategi A, Mian SA, Passaro D, Rouault-Pierre K, Grey W, Bonnet D.

J Exp Med. 2018 Mar 5;215(3):729-743. doi: 10.1084/jem.20172139. Epub 2018 Feb 16. Review.

PMID: 29453226

2017 - 2016

Increased Vascular Permeability in the Bone Marrow Microenvironment Contributes to Disease Progression and Drug Response in Acute Myeloid Leukemia.

Passaro D, Di Tullio A, Abarrategi A, Rouault-Pierre K, Foster K, Ariza-McNaughton L, Montaner B, Chakravarty P, Bhaw L, Diana G, Lassailly F, Gribben J, Bonnet D.

Cancer Cell. 2017 Sep 11;32(3):324-341.e6. doi: 10.1016/j.ccell.2017.08.001. Epub 2017 Sep 1.

PMID: 28870739

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Bioengineering of Humanized Bone Marrow Microenvironments in Mouse and Their Visualization by Live Imaging.

Passaro D, Abarrategi A, Foster K, Ariza-McNaughton L, Bonnet D.

J Vis Exp. 2017 Aug 1;(126). doi: 10.3791/55914.

PMID: 28809828

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Versatile humanized niche model enables study of normal and malignant human hematopoiesis.

Abarrategi A, Foster K, Hamilton A, Mian SA, Passaro D, Gribben J, Mufti G, Bonnet D.

J Clin Invest. 2017 Feb 1;127(2):543-548. doi: 10.1172/JCI89364. Epub 2017 Jan 9.

PMID: 28067666

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T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments.

Hawkins ED, Duarte D, Akinduro O, Khorshed RA, Passaro D, Nowicka M, Straszkowski L, Scott MK, Rothery S, Ruivo N, Foster K, Waibel M, Johnstone RW, Harrison SJ, Westerman DA, Quach H, Gribben J, Robinson MD, Purton LE, Bonnet D, Lo Celso C.

Nature. 2016 Oct 27;538(7626):518-522. doi: 10.1038/nature19801. Epub 2016 Oct 17.

PMID: 27750279

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Microenvironmental cues for T-cell acute lymphoblastic leukemia development.

Passaro D, Quang CT, Ghysdael J.

Immunol Rev. 2016 May;271(1):156-72. doi: 10.1111/imr.12402. Review.

PMID: 27088913

2015 - 2014

Calcineurin/CXCR4 in T-ALL.

Passaro D, Quang CT, Ghysdael J.

Oncoscience. 2015 Sep 12;2(10):781-2. eCollection 2015. No abstract available.

PMID: 26682242

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CXCR4 Is Required for Leukemia-Initiating Cell Activity in T Cell Acute Lymphoblastic Leukemia.

Passaro D, Irigoyen M, Catherinet C, Gachet S, Da Costa De Jesus C, Lasgi C, Tran Quang C, Ghysdael J.

Cancer Cell. 2015 Jun 8;27(6):769-79. doi: 10.1016/j.ccell.2015.05.003.

PMID:

26058076

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Interleukin-18 produced by bone marrow-derived stromal cells supports T-cell acute leukaemia progression.

Uzan B, Poglio S, Gerby B, Wu CL, Gross J, Armstrong F, Calvo J, Cahu X, Deswarte C, Dumont F, Passaro D, Besnard-Guérin C, Leblanc T, Baruchel A, Landman-Parker J, Ballerini P, Baud V, Ghysdael J, Baleydier F, Porteu F, Pflumio F.

EMBO Mol Med. 2014 Jun;6(6):821-34. doi: 10.1002/emmm.201303286. Epub 2014 Apr 6.

PMID: 24778454

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